Aims

This module addresses doctoral students in chemistry, physics, biophysics, and related fields with prior knowledge in NMR spectroscopy. It focuses on the advanced theoretical and technical concepts of high-field NMR.

Contents

Each day of the two-day program starts with a series of lectures in the morning, followed by hands-on experiments

Lectures:

• Average Hamiltonian Theory: Formal treatment and examples such as description of magic-angle spinning
• Concepts of rotational and rotary resonance; SIMPSON simulations
• Heteronuclear dipolar decoupling:  theory, design, and explanation of the      prominent pulse schemes; numerical simulation of all these with SIMPSON; factors affecting resolution; spin-diffusion effect
• Heteronuclear dipolar recoupling: symmetry-adapted schemes; SIMPSON simulations; typical schemes such as PDSD, DARR, PARIS, and MIRROR.
• Solid-state NMR of quadrupolar spins
• High-resolution methods for protons in solid-state NMR and SIMPSON simulations of the pulse schemes

Hands-on lab course:

• SIMPSON simulation of various pulse sequences

Recommendations for literature, e-learning

• Klaus Schmidt-Rohr & Hans Wolfgang Spiess, Multidimensional Solid-State NMR and Polymers, Academic Press, London, 1994
• Melinda J. Duer, Introduction to Solid-State NMR Spectroscopy, Blackwell Publishing, Oxford, 2004
• David D. Laws, Hans-Marcus L. Bitter, and Alexej Jerschow Solid-State NMR Spectroscopic Methods in Chemistry Angew. Chem. Int. Ed. 2002, 41, 3096 – 3129
• Alexej Jerschow From nuclear structure to the quadrupolar NMR interactionand high-resolution spectroscopy Progress in Nuclear Magnetic Resonance Spectroscopy 46 (2005) 63–78

Terms and Applications

• Date: June 24-25, 2013
• Time: 9am-4.30pm
• Venue: Härtelstr. 16-18, Leipzig
• Group size: maximal 10
• Language: English

Instructors

P. K. Madhu, D. Huster

Schedule

Monday, 24 June 2013

Härtelstr. 16-18, room 017

9:00 – 10:30    1^st Lecture
10:30 – 11:00  Coffee Break
11:00 – 12:30  2^nd Lecture

Härtelstr. 16-18, room 015.2

12:30 – 13:30 Lunch Break
13:30 - 16:30   Simulation Tutorial with Simpson Part I including coffee break

Tuesday, 25 June 2013

Härtelstr. 16-18, room 018

9:00 – 10:30    3^rd Lecture
10:30 – 11:00  Coffee Break
11:00 – 12:30  4^th Lecture
12:30 – 13:30 Lunch Break

Härtelstr. 16-18, room 015.2

13:30 - 16:30   Simulation Tutorial with Simpson Part II including coffee break